2/12/2019 · 8. AH are prodrugs except . a) Enalapril . b) Paracetamol . c) Sulphamethoxazole . d) Trimethoprim . Ans:d . 9.Which drug has a high first pass effect. a) Amiodarone. b) Phenytoin. c) Verapamil. d) Disopyramide. Ans:c . 10. AH of the following do not cross the blood brain barrier except . a) Pyridostigmine, Enalapril maleate is the maleate salt of enalapril , a derivative of two amino acids, L-alanine and L-proline. Enalapril maleate is a prodrug which when administered orally is hydrolysed to release a specific, long acting angiotensin converting enzyme (ACE) inhibitor, enalaprilat.
Medical uses. Spironolactone is used primarily to treat heart failure, edematous conditions such as nephrotic syndrome or ascites in people with liver disease, essential hypertension, low blood levels of potassium, secondary hyperaldosteronism (such as occurs with liver cirrhosis ), and Conn’s syndrome (primary hyperaldosteronism).
10/13/2020 · Simvastatin is a prodrug and is hydrolyzed to its active ?-hydroxyacid form, simvastatin acid, after administration. Simvastatin is a specific inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate limiting step in the biosynthetic pathway for.
230. All of the following drugs act as prodrugs and need to be converted in the body to active compound, except : a. levodopa c. prednisone e. cyclophosphamide b. salbutamol d. bacampicillin, 10/22/2020 · 1. Paracetamol (acetaminophen) 2 . Diclofenac 3. Predinisolone 4. Celecoxib 69. Which of the following drugs is not useful in tuberculous meningitis: 1. Rifampicin 2 . Streptomycin 3. Isoniazid 4. Pyrazinamide 70. Selectively of action of Metronidazole for anaerobes is due to: 1. Presence of ferridoxin in anaerobes 2 . Greater uptake of drug by anaerobes 3.
Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis ( except for in the first trimester of pregnancy) and the patient’s sexual partners, bacterial vaginosis 16, certain types of amebiasis, and various anaerobic infections. 11 The above anaerobic infections may occur on the skin and skin structures, the abdomen, the heart, …
